Prof. Dr. rer. nat. habil

Ute Marx





Di. 9:45 - 11:15 Uhr, Raum T2.4.17


(07231) 28-6519



2012 - Master of Business Administration, Other
Hochschule Landshut

2003 - Habilitation, Natural Sciences
Universität Bayreuth

1996 - Dr. rer. nat., Natural Sciences
Universität Bayreuth

1993 - Diplom (Universitaet), Natural Sciences
Universität Bayreuth

since 2015 - Hochschule Pforzheim - Germany


2008 - 2015 - Bruker BioSpin GmbH - Germany


2004 - 2008 - University of Queensland - Australia

Senior Research Officer

since 2003 - Universität Bayreuth - Germany


2000 - 2004 - Universität Bayreuth - Germany



Preis des Universitätsvereins der Universität Bayreuth zur Förderung des wissenschaftlichen Nachwuchses

2000 - 2003

Bayerischer Habilitationsförderpreis


Auszeichnung durch den Fonds der Chemischen Industrie: Anerkennung sehr guter Leistungen und eines zügigen Studienabschlusses

1994 - 1996

Stipendiatin bzw. Assoziierte des Graduiertenkollegs "Biosynthese der Proteine und Regulation ihrer Aktivität"

Marketing ,  Other

Journal article

PALESCH, D., VARGA, E., MARX, U., VITZITHUM, K., KREUTZMANN, P., FORSSMANN, W.-G., ... MÄGERT, H.-J. (2013). Domain 15 of the serine proteinase inhibitor LEKTI blocks HIV infection in vitro. Medical Journal of Indonesia, 22 (3), 131-135.

KELLER, M., POLLITT, C., & MARX, U. (2011). Nuclear magnetic resonance-based metabonomic study of early time point laminitis in an oligofructose-overload model. Equine Veterinary Journal, 43, pp. 737-743.

SPRAUL, M., SCHÜTZ, B., RINKE, P., KOSWIG, S., HUMPFER, E., SCHÄFER, H., ... MINOJA, A. (2009). NMR-Based Multi Parametric Quality Control of Fruit Juices: SGF Profiling. Nutrients, 1, 148-155.

TIMMINS, M., ZHOU, W., RUPPRECHT, J., LIM, L., THOMAS-HALL, S., DOEBBE, A., ... SCHENK, P. (2009). The Metabolome of Chlamydomonas reinhardtii following Induction of Anaerobic H2 Production by Sulfur Depletion. The Journal of Biological Chemistry (284), 23415-23425.

TIMMINS, M., THOMAS-HALL, S., DARLING, A., ZHANG, E., MARX, U., HANKAMER, B., & SCHENK, P. (2009). Phylogenetic and molecular analysis of hydrogen-producing green algae. Journal of Experimental Botany, 60, 1691-1702.

DALY, N., CHEN, Y., ROSENGREN, K., MARX, U., PHILLIPS, M., WARING, A., ... CRAIK, D. (2009). Retrocyclin-2: a potent anti-HIV theta-defensin that forms a cyclic cystine ladder structural motif.. Advances in Experimental Medicine and Biology, 611, 577-578.

LAUBER, T., TIDTEN, N., MATECKO, I., ZEEB, M., RÖSCH, P., & MARX, U. (2009). Design and characterization of a soluble fragment of the extracellular ligand-binding domain of the peptide hormone receptor guanylyl cyclase-C.. Protein Engineering, Design and Selection, 22, 1-7.

RODDA , C. P., MARX, U., WELLARD, R., MCCREDIE, D., PELL, G., PITT, J., ... STRAUSS, B. (2009). Osteopaenia in a teenage boy presenting with previously undiagnosed guanidinoacetate methyltransferase (GAMT) deficiency and response to creatine supplementation. BONE, 45, 2.

SCHENK, P. M., MARX, U., THOMAS-HALL, S. R., STEPHENS, E., MUSSGNUG , J. H., POSTEN, C., ... HANKAMER, B. (2009). Second Generation Biofuels: High-Efficiency Microalgae for Biodiesel Production. BioEnergy Research, 1 (1), pp. 20-43.

VITZITHUM, K., LAUBER, T., KREUTZMANN, P., SCHULZ, A., SOMMERHOFF, C., RÖSCH, P., & MARX, U. (2008). LEKTI domain 15 is a functional Kazal-type proteinase inhibitor. PROTEIN EXPRESSION AND PURIFICATION, 2007 (57(1)), 45-56.

SCHENK, P., THOMAS-HALL, S., STEVENS, E., MARX, U., MUSSGNUG, J., POSTEN, C., ... HANKAMER, B. (2008). Second Generation Biofuels: High-efficiency microalgae for biodiesel production. BioEnergy Research, 1, 20-43.

DALY, N., CHEN, Y., ROSENGREN, K., MARX, U., PHILLIPS, M., WARING, A., ... CRAIK, D. (2007). Retrocyclin-2: Structural Analysis of a Potent Anti-HIV theta-Defensin. BIOCHEMISTRY, 46, 9920-9928.

MARX, U., DALY, N., & CRAIK, D. (2006). NMR of conotoxins: structural features and an analysis of chemical shifts of post-translationally modified amino acids. Magnetic Resonance in Chemistry.

EGELRUD, T., BRATTSAND, M., KREUTZMANN, P., WALDEN, M., VITZITHUM, K., MARX, U., ... MÄGERT, H. (2005). hK5 and hK7, two serine proteinases abundant in human skin, are inhibited by LEKTI domain 6. British Journal of Dermatology, 153, 1200-1203.

LAUBER, T., & MARX, U. (2005). Prosequence-mediated disulfide coupled folding of the peptide hormones guanylin and uroguanylin. Protein & Peptide Letters, 12, 153-158.

SCHULZ, A., MARX, U., TIDTEN, N., LAUBER, T., HIDAKA, Y., & ADERMANN, K. (2005). Side chain contributions to the interconversion of the topological isomers of guanylin-like peptides. Journal of Peptide Science, 11, 319-330.

JAYAKUMAR, A., KANG, Y., MITSUDO, K., HENDERSON, Y., FREDERICK, M., WANG, M., ... CLAYMAN, G. (2004). Expression of LEKTI domains 6-9' in the baculovirus expression system: recombinant LEKTI domains 6-9' inhibit trypsin and subtilisin A. Protein Expression and Purification, 35, 93-101.

LAUBER, T., SCHULZ, A., RÖSCH, P., & MARX, U. (2004). Role of disulfide bonds for the structure and folding of proguanylin. BIOCHEMISTRY, 43, 10050-10057.

TIDOW, H., LAUBER, T., VITZITHUM, K., SOMMERHOFF, C., RÖSCH, P., & MARX, U. (2004). The solution structure of a chimeric LEKTI domain reveals a chameleon sequence. BIOCHEMISTRY, 43, 11238-11247.

LAUBER, T., NEUDECKER, P., RÖSCH, P., & MARX, U. (2003). Solution structure of human proguanylin: the role of a hormone prosequence. The Journal of Biological Chemistry, 278, 24118-24124.

LAUBER, T., SCHULZ, A., SCHWEIMER, K., ADERMANN, K., & MARX, U. (2003). Homologous proteins with different folds: the three-dimensional structures of domains 1 and 6 of the multiple Kazal-type inhibitor LEKTI. Journal of Molecular Biology, 328, pp. 328: 205-219.

MARX, U., KORSINCZKY, M., SCHIRRA, H., JONES, A., CONDIE, B., OTVOS, L. J., & CRAIK, D. (2003). Enzymatic cyclization of a potent bowman-birk protease inhibitor, sunflower trypsin inhibitor-1, and solution structure of an acyclic precursor peptide. The Journal of Biological Chemistry, 278, 21782-21789.

ZIEGLER, J., STICHT, H., MARX, U., MÜLLER, W., RÖSCH, P., & SCHWARZINGER, S. (2003). D and NMR studies of prion protein (PrP) helix 1. Novel implications for its role in the PrPC-->PrPSc conversion process. The Journal of Biological Chemistry, 278, 50175-50181.

LAUBER, T., NOURSE, A., SCHULZ, A., & MARX, U. (2002). Native and recombinant proguanylin feature identical biophysical properties and are monomeric in solution. BIOCHEMISTRY, 41, 14602-14612.

LAUBER, T., MARX, U., SCHULZ, A., KREUTZMANN, P., RÖSCH, P., & HOFFMANN, S. (2001). Accurate disulfide formation in Escherichia coli: overexpression and characterization of the first domain (HF6478) of the multiple Kazal-type inhibitor LEKTI. Protein Expression and Purification, 22, 108-112.

MARX, U., ADERMANN, K., BAYER, P., FORSSMANN, W., & RÖSCH, P. (2000). Solution structures of human parathyroid hormone fragments hPTH(1-34) and hPTH(1-39) and bovine parathyroid hormone fragment bPTH(1-37). Biochemical and Biophysical Research Communications, 267, 213-220.

URBAN, S., SCHWARZ, C., MARX, U., ZENTGRAF, H., SCHALLER, H., & MULTHAUP, G. (2000). Receptor recognition by a hepatitis B virus reveals a novel mode of high affinity virus-receptor interaction. EMBO JOURNAL, 19, 1217-1227.

SCHULZ, A., MARX, U., HIDAKA, Y., SHIMONISHI, Y., RÖSCH, P., FORSSMANN, W., & ADERMANN, K. (1999). Role of the prosequence of guanylin. PROTEIN SCIENCE, 8, 1850-1859.

WEIDLER, M., MARX, U., SEIDEL, G., SCHÄFER, W., HOFFMANN, E., ESSWEIN, A., & RÖSCH, P. (1999). The structure of human parathyroid hormone-related protein(1-34) in near-physiological solution. FEBS LETTERS, 444, 239-244.

MARX, U., ADERMANN, K., BAYER, P., MEYER, M., FORSSMANN, W., & RÖSCH, P. (1998). Structure-activity relation of NH2-terminal human parathyroid hormone fragments. The Journal of Biological Chemistry, 273, 4308-4316.

MARX, U., KLODT, J., MEYER, M., GERLACH, H., RÖSCH, P., FORSSMANN, W., & ADERMANN, K. (1998). One peptide, two topologies: structure and interconversion dynamics of human uroguanylin isomers. Journal of Peptide Research, 52, pp. 229-240.

SCHULZ, A., ESCHER, S., MARX, U., MEYER, M., RÖSCH, P., FORSSMANN, W., & ADERMANN, K. (1998). Carboxy-terminal extension stabilises the topological stereoisomers of guanylin. Journal of Peptide Research, 52, 518-525.

KLODT, J., KUHN, M., MARX, U., MARTIN, S., RÖSCH, P., FORSSMANN, W., & ADERMANN, K. (1997). Synthesis, biological activity and isomerism of guanylate cyclase C-activating peptides guanylin and uroguanylin. Journal of Peptide Research, 50, pp. 222-230.

MARX, U., AUSTERMANN, S., BAYER, P., ADERMANN, K., EJCHART, A., STICHT, H., ... RÖSCH, P. (1995). Structure of human parathyroid hormone 1-37 in solution. The Journal of Biological Chemistry, 270, 15194-15202.

Article in Proceeding

MARX, U., MEINKE, M., WELLARD, R., AMMINGER, P., PROFFITT, T., WOOD, S., ... BERGER, G. (2017). Metabonomic Study of Schizophrenia Using High-Resolution NMR Spectroscopy. In Metabolomics Scociety (Ed.), Metabolomics 2017, 13th Annual Conference of the Metabolomics Society (pp. 101).